Mouse Tnnt1 activation kit by CRISPRa

CAT#: GA204406

Tnnt1 CRISPRa kit - CRISPR gene activation of mouse troponin T1, skeletal, slow

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Tnnt1
• Locus ID: 21955
• Kit Components:

  GA204406G1, Tnnt1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204406G2, Tnnt1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204406G3, Tnnt1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001277903, NM_001277904, NM_011618, NM_001360154
• Synonyms: AW146156; ssTnT; sTnT; Tnt
• Summary: This gene encodes the slow skeletal tropomyosin-binding subunit of the troponin complex and plays an essential role in the regulation of striated muscle contraction. In humans, mutations in this gene are associated with nemaline myopathy type 5. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2013]