Mouse Hgfac activation kit by CRISPRa

CAT#: GA205711

Hgfac CRISPRa kit - CRISPR gene activation of mouse hepatocyte growth factor activator

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Hgfac
• Locus ID: 54426
• Kit Components:

  GA205711G1, Hgfac gRNA vector 1 in pCas-Guide-CRISPRa

  GA205711G2, Hgfac gRNA vector 2 in pCas-Guide-CRISPRa

  GA205711G3, Hgfac gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019447
• Synonyms: HGFA
• Summary: This gene encodes a serine protease enzyme that proteolytically activates hepatocyte growth factor (HGF) and plays a vital role in the regulation of HGF activity in the regeneration and repair of various tissues. The encoded protein is an inactive zymogen that is proteolytically activated to generate a heterodimeric enzyme consisting of a short chain and a long chain linked by a disulfide bridge. Mice lacking the encoded protein display an impairment in mucosal regeneration after injury. [provided by RefSeq, Jul 2015]