Mouse Prdx5 activation kit by CRISPRa

CAT#: GA205761

Prdx5 CRISPRa kit - CRISPR gene activation of mouse peroxiredoxin 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Prdx5
• Locus ID: 54683
• Kit Components:

  GA205761G1, Prdx5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA205761G2, Prdx5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA205761G3, Prdx5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_012021, NM_001358444
• Synonyms: AOEB166; AOPP; Pmp20; Prdx6; PrxV
• Summary: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. The use of alternate transcription start sites may result in use of alternate in-frame translation start codons that generate alternate isoforms that are targeted to the mitochondrion or peroxisome/cytoplasm. [provided by RefSeq, Nov 2017]