Mouse Enpp6 activation kit by CRISPRa

CAT#: GA216597

Enpp6 CRISPRa kit - CRISPR gene activation of mouse ectonucleotide pyrophosphatase/phosphodiesterase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Enpp6
• Locus ID: 320981
• Kit Components:

  GA216597G1, Enpp6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA216597G2, Enpp6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA216597G3, Enpp6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_177304
• Synonyms: 4833421B01Rik; B830047L21Rik; D8Ertd514e; E-NPP 6; GPC-Cpde; Npp6
• Summary: This gene encodes a member of the nucleotide pyrophosphatase/phosphodiesterase family of enzymes that play an important role in regulating extracellular nucleotide metabolism. The encoded preproprotein undergoes proteolytic processing to generate a glycosylphosphatidylinositol (GPI)-anchored membrane protein that hydrolyzes choline-containing lysophospholipids such as glycerophosphocholine. Mice lacking the encoded protein develop fatty liver and myelin sheath abnormalities. [provided by RefSeq, Jul 2016]