GDNF Receptor alpha 1 (GFRA1) Human Gene Knockout Kit (CRISPR)
CAT#: KN204866RB
GFRA1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | GDNF Receptor alpha 1 |
Locus ID | 2674 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001145453, NM_005264, NM_145793, NM_001348096, NM_001348097, NM_001348098, NM_001348099 |
Synonyms | GDNFR; GDNFRA; GFR-ALPHA-1; RET1L; RETL1; TRNR1 |
Summary | 'This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN204866 | GFRA1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN204866BN | GFRA1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN204866LP | GFRA1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN404866 | GFRA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA101786 | GFRA1 CRISPRa kit - CRISPR gene activation of human GDNF family receptor alpha 1 |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review