Occludin (OCLN) Human Gene Knockout Kit (CRISPR)
CAT#: KN206468
OCLN - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | OCLN |
Locus ID | 100506658 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001205254, NM_001205255, NM_002538 |
Synonyms | BLCPMG; PPP1R115 |
Summary | This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN206468BN | OCLN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN206468LP | OCLN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN206468RB | OCLN - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN406468 | OCLN - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA119306 | OCLN CRISPRa kit - CRISPR gene activation of human occludin |
USD 1,290.00 |
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