LZTFL1 Human Gene Knockout Kit (CRISPR)
CAT#: KN207289LP
LZTFL1 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | Luciferase-Puro |
Symbol | LZTFL1 |
Locus ID | 54585 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001276378, NM_001276379, NM_020347, NR_075080 |
Synonyms | BBS17 |
Summary | This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013] |
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN207289 | LZTFL1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN207289BN | LZTFL1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN207289RB | LZTFL1 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN407289 | LZTFL1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA110191 | LZTFL1 CRISPRa kit - CRISPR gene activation of human leucine zipper transcription factor like 1 |
USD 1,290.00 |
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