Tuberin (TSC2) Human Gene Knockout Kit (CRISPR)

CAT#: KN211461RB

TSC2 - human gene knockout kit via CRISPR, HDR mediated


HDR-mediated knockout kit validation

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USD 1,290.00

4 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Tuberin
Locus ID 7249
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000548, NM_001077183, NM_001114382, NM_001318827, NM_001318829, NM_001318831, NM_001318832, NM_021055, NM_021056, NM_001363528, NM_001370405, NM_001370404
Synonyms LAM; PPP1R160; TSC4
Summary 'Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.