JMJD1C Human Gene Knockout Kit (CRISPR)
CAT#: KN214878BN
JMJD1C - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | JMJD1C |
Locus ID | 221037 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001282948, NM_001318153, NM_001318154, NM_004241, NM_032776, NR_134512, NM_001322252, NM_001322254, NM_001322258 |
Synonyms | TRIP8 |
Summary | The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
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KN214878 | JMJD1C - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN214878LP | JMJD1C - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN214878RB | JMJD1C - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN414878 | JMJD1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA116586 | JMJD1C CRISPRa kit - CRISPR gene activation of human jumonji domain containing 1C |
USD 1,290.00 |
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