KDM5B Human Gene Knockout Kit (CRISPR)
CAT#: KN214918RB
KDM5B - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | KDM5B |
Locus ID | 10765 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_006618, NM_001314042, NM_001347591 |
Synonyms | CT31; JARID1B; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A |
Summary | This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016] |
Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN214918 | KDM5B - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN214918BN | KDM5B - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN214918LP | KDM5B - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN414918 | KDM5B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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GA107375 | KDM5B CRISPRa kit - CRISPR gene activation of human lysine demethylase 5B |
USD 1,290.00 |
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