TNFRSF18 Human Gene Knockout Kit (CRISPR)
CAT#: KN219997BN
TNFRSF18 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | TNFRSF18 |
Locus ID | 8784 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_004195, NM_148901, NM_148902 |
Synonyms | AITR; CD357; GITR; GITR-D |
Summary | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN219997 | TNFRSF18 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN219997LP | TNFRSF18 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN219997RB | TNFRSF18 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN419997 | TNFRSF18 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA105831 | TNFRSF18 CRISPRa kit - CRISPR gene activation of human TNF receptor superfamily member 18 |
USD 1,290.00 |
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