BRD2 Human Gene Knockout Kit (CRISPR)
CAT#: KN220612
BRD2 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | BRD2 |
Locus ID | 6046 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001113182, NM_001199455, NM_001199456, NM_001291986, NM_005104, NR_037625 |
Synonyms | D6S113E; FSH; FSRG1; NAT; RING3; RNF3 |
Summary | 'This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN220612BN | BRD2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN220612LP | BRD2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN220612RB | BRD2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN420612 | BRD2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA104119 | BRD2 CRISPRa kit - CRISPR gene activation of human bromodomain containing 2 |
USD 1,290.00 |
{0} Product Review(s)
Be the first one to submit a review