TREM2 Human Gene Knockout Kit (CRISPR)
CAT#: KN221132BN
TREM2 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | mBFP-Neo |
Symbol | TREM2 |
Locus ID | 54209 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001271821, NM_018965 |
Synonyms | TREM-2; Trem2a; Trem2b; Trem2c |
Summary | This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012] |
Documents
Product Manuals |
FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN221132 | TREM2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN221132LP | TREM2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN221132RB | TREM2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN421132 | TREM2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA110075 | TREM2 CRISPRa kit - CRISPR gene activation of human triggering receptor expressed on myeloid cells 2 |
USD 1,290.00 |
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