TIMM50 Human Gene Knockout Kit (CRISPR)
CAT#: KN224744
TIMM50 - human gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
USD 1,290.00
4 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control |
Donor DNA | GFP-puro |
Symbol | TIMM50 |
Locus ID | 92609 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001001563, NM_001329559 |
Synonyms | TIM50; TIM50L |
Summary | This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN224744BN | TIMM50 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN224744LP | TIMM50 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN224744RB | TIMM50 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN424744 | TIMM50 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
|
GA114227 | TIMM50 CRISPRa kit - CRISPR gene activation of human translocase of inner mitochondrial membrane 50 |
USD 1,290.00 |
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