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Lysyl tRNA synthetase (KARS) Human Gene Knockout Kit (CRISPR)
CAT#: KN400311
KARS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN400311 is the updated version of KN200311.
USD 1,290.00
2 Weeks*
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Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 linear donor |
| Donor DNA | EF1a-GFP-P2A-Puro |
| Symbol | Lysyl tRNA synthetase |
| Locus ID | 3735 |
| Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_001130089, NM_005548 |
| Synonyms | CMTRIB; DFNB89; KARS1; KARS2; KRS |
| Summary | 'Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]' |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| GA102512 | KARS CRISPRa kit - CRISPR gene activation of human lysyl-tRNA synthetase |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.