HMGA1 Human Gene Knockout Kit (CRISPR)

CAT#: KN401458

HMGA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: HMGA1
• Locus ID: 3159
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001319077, NM_001319078, NM_001319079, NM_001319080, NM_001319081, NM_001319082, NM_002131, NM_145899, NM_145901, NM_145902, NM_145903, NM_145904, NM_145905
• Synonyms: HMG-R; HMGA1A; HMGIY
• Summary: 'This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016]'