Serine Palmitoyltransferase (SPTLC2) Human Gene Knockout Kit (CRISPR)

CAT#: KN402420

SPTLC2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN402420 is the updated version of KN202420.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol SPTLC2
Locus ID 9517
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_004863
Synonyms hLCB2a; HSN1C; LCB2; LCB2A; NSAN1C; SPT2
Summary This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]

Other Versions

SKU Description Size Price
GA106363 SPTLC2 CRISPRa kit - CRISPR gene activation of human serine palmitoyltransferase long chain base subunit 2
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.