SETDB1 Human Gene Knockout Kit (CRISPR)
CAT#: KN403647
SETDB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN403647 is the updated version of KN203647.
USD 1,290.00
2 Weeks*
Size
Other products for "SETDB1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | SETDB1 |
Locus ID | 9869 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001145415, NM_001243491, NM_012432, NR_026977, NM_001366417, NM_001366418 |
Synonyms | ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21 |
Summary | This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jun 2011] |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA106659 | SETDB1 CRISPRa kit - CRISPR gene activation of human SET domain bifurcated histone lysine methyltransferase 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.