PHLPP (PHLPP1) Human Gene Knockout Kit (CRISPR)
CAT#: KN403930
PHLPP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN403930 is the updated version of KN203930.
USD 1,290.00
2 Weeks*
Size
Other products for "PHLPP1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | PHLPP1 |
Locus ID | 23239 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_194449 |
Synonyms | PHLPP; PLEKHE1; PPM3A; SCOP |
Summary | This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011] |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA108152 | PHLPP1 CRISPRa kit - CRISPR gene activation of human PH domain and leucine rich repeat protein phosphatase 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.