Apoptosis inhibitor 5 (API5) Human Gene Knockout Kit (CRISPR)
CAT#: KN404435
API5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN404435 is the updated version of KN204435.
USD 1,290.00
2 Weeks*
Size
Other products for "API5"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | API5 |
Locus ID | 8539 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001142930, NM_001142931, NM_001243747, NM_006595, NR_024625 |
Synonyms | AAC-11; AAC11 |
Summary | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA105653 | API5 CRISPRa kit - CRISPR gene activation of human apoptosis inhibitor 5 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.