MAP2K1IP1 (LAMTOR3) Human Gene Knockout Kit (CRISPR)
CAT#: KN404668
LAMTOR3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN404668 is the updated version of KN204668.
USD 1,290.00
2 Weeks*
Size
Other products for "LAMTOR3"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | LAMTOR3 |
Locus ID | 8649 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001243736, NM_021970, NR_024170 |
Synonyms | MAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3 |
Summary | This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA105732 | LAMTOR3 CRISPRa kit - CRISPR gene activation of human late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.