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PCK1 Human Gene Knockout Kit (CRISPR)
CAT#: KN404758
PCK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN404758 is the updated version of KN204758.
USD 1,290.00
2 Weeks*
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Specifications
| Product Data | |
| Format | 2 gRNA vectors, 1 linear donor |
| Donor DNA | EF1a-GFP-P2A-Puro |
| Symbol | PCK1 |
| Locus ID | 5105 |
| Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
| Reference Data | |
| RefSeq | NM_002591 |
| Synonyms | PEPCK-C; PEPCK1; PEPCKC |
| Summary | 'This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008]' |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| GA103414 | PCK1 CRISPRa kit - CRISPR gene activation of human phosphoenolpyruvate carboxykinase 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.