HACE1 Human Gene Knockout Kit (CRISPR)

CAT#: KN405602

HACE1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.



KN2.0 knockout kit validation

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KN405602 is the updated version of KN205602.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol HACE1
Locus ID 57531
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_020771, NR_104424, NM_001321080, NM_001321083, NM_001321084, NM_001350554, NM_001350555, NM_001350556, NM_001350557, NM_001350558, NM_001350559, NM_001350560, NR_146787, NR_146788, NR_146789, NR_146790, NR_146791, NR_146792
Synonyms HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
Summary This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.