PRPSAP2 Human Gene Knockout Kit (CRISPR)

CAT#: KN410719

PRPSAP2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

• 

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: PRPSAP2
• Locus ID: 5636
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001243936, NM_001243940, NM_001243941, NM_001243942, NM_002767, NM_001353096, NM_001353097, NM_001353098, NM_001353099, NM_001353100, NM_001353101, NM_001353102, NM_001353103, NM_001353104, NM_001353105, NM_001353106, NM_001353107
• Synonyms: PAP41
• Summary: 'This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]'