MCOLN2 Human Gene Knockout Kit (CRISPR)

CAT#: KN411195

MCOLN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN411195 is the updated version of KN211195.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol MCOLN2
Locus ID 255231
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_153259, NM_001330647
Synonyms TRP-ML2; TRPML2
Summary Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]). [supplied by OMIM, Sep 2009]

Other Versions

SKU Description Size Price
GA116814 MCOLN2 CRISPRa kit - CRISPR gene activation of human mucolipin 2
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.