Rho GTPase activating protein 24 (ARHGAP24) Human Gene Knockout Kit (CRISPR)

CAT#: KN411832

ARHGAP24 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN411832 is the updated version of KN211832.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol ARHGAP24
Locus ID 83478
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001025616, NM_001042669, NM_001287805, NM_031305, NM_001346093
Synonyms FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
Summary This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Other Versions

SKU Description Size Price
GA113184 ARHGAP24 CRISPRa kit - CRISPR gene activation of human Rho GTPase activating protein 24
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.