PAX2 Human Gene Knockout Kit (CRISPR)
CAT#: KN411996
PAX2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | PAX2 |
Locus ID | 5076 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000278, NM_001304569, NM_003987, NM_003988, NM_003989, NM_003990 |
Synonyms | FSGS7; PAPRS |
Summary | 'PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN211996 | PAX2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN211996BN | PAX2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN211996LP | PAX2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
KN211996RB | PAX2 - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
|
GA103390 | PAX2 CRISPRa kit - CRISPR gene activation of human paired box 2 |
USD 1,290.00 |
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