RPGR Human Gene Knockout Kit (CRISPR)
CAT#: KN412243
RPGR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN412243 is the updated version of KN212243.
USD 1,290.00
2 Weeks*
Size
Other products for "RPGR"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | RPGR |
Locus ID | 6103 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_000328, NM_001023582, NM_001034853, NM_001367245, NM_001367246, NM_001367249, NM_001367250, NM_001367251, NR_159804, NR_159807, NR_159808, NM_001367247, NM_001367248, NR_159803, NR_159805, NR_159806 |
Synonyms | COD1; CORDX1; CRD; orf15; PCDX; RP3; RP15; XLRP3 |
Summary | 'This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined. [provided by RefSeq, Dec 2008]' |
Documents
Product Manuals |
FAQs |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA104137 | RPGR CRISPRa kit - CRISPR gene activation of human retinitis pigmentosa GTPase regulator |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.