PDE8B Human Gene Knockout Kit (CRISPR)

CAT#: KN414247

PDE8B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN414247 is the updated version of KN214247.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol PDE8B
Locus ID 8622
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001029851, NM_001029852, NM_001029853, NM_001029854, NM_003719, NM_001349748, NM_001349749, NM_001349750, NM_001349751, NM_001349752, NM_001349753
Synonyms ADSD; PPNAD3
Summary The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Other Versions

SKU Description Size Price
GA105708 PDE8B CRISPRa kit - CRISPR gene activation of human phosphodiesterase 8B
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.