CCBL1 (KYAT1) Human Gene Knockout Kit (CRISPR)

CAT#: KN416317

KYAT1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

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Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: CCBL1
• Locus ID: 883
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001122671, NM_001122672, NM_001287390, NM_004059, NR_109829, NM_001352988, NM_001352989, NM_001352990, NM_001352991, NM_001352992, NM_001352993, NM_001352994, NM_001352995, NM_001352996, NM_001352997, NM_001352998, NM_001352999, NR_148224, NR_148225
• Synonyms: CCBL1; GTK; KAT1; KATI
• Summary: 'This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'