LTBP4 Human Gene Knockout Kit (CRISPR)

CAT#: KN416878

LTBP4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN416878 is the updated version of KN216878.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol LTBP4
Locus ID 8425
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001042544, NM_001042545, NM_003573
Synonyms ARCL1C; LTBP-4; LTBP4L; LTBP4S
Summary The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Other Versions

SKU Description Size Price
GA105563 LTBP4 CRISPRa kit - CRISPR gene activation of human latent transforming growth factor beta binding protein 4
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.