Bile Acid Receptor (NR1H4) Human Gene Knockout Kit (CRISPR)

CAT#: KN417443

NR1H4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN417443 is the updated version of KN217443.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol NR1H4
Locus ID 9971
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001206977, NM_001206978, NM_001206979, NM_001206992, NM_001206993, NM_005123, NR_135146
Synonyms BAR; FXR; HRR-1; HRR1; PFIC5; RIP14
Summary This gene encodes a ligand-activated transcription factor that shares structural features in common with nuclear hormone receptor family members. This protein functions as a receptor for bile acids, and when bound to bile acids, binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]

Other Versions

SKU Description Size Price
GA106749 NR1H4 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 1 group H member 4
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.