TRIF (TICAM1) Human Gene Knockout Kit (CRISPR)
CAT#: KN417522
TICAM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN417522 is the updated version of KN217522.
USD 1,290.00
2 Weeks*
Size
Other products for "TICAM1"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | TICAM1 |
Locus ID | 148022 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_014261, NM_182919 |
Synonyms | MGC35334; PRVTIRB; TICAM-1; TIR domain-containing adaptor molecule 1; TIR domain containing adaptor inducing interferon-beta; toll-like receptor adaptor molecule 1; TRIF; TRIF, PRVTIRB, TICAM-1, MGC35334 |
Summary | This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. [provided by RefSeq, Jan 2012] |
Documents
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FAQs |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA115649 | TICAM1 CRISPRa kit - CRISPR gene activation of human toll like receptor adaptor molecule 1 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.