SLC39A14 Human Gene Knockout Kit (CRISPR)
CAT#: KN417966
SLC39A14 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN417966 is the updated version of KN217966.
USD 1,290.00
2 Weeks*
Size
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Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | SLC39A14 |
Locus ID | 23516 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001128431, NM_001135153, NM_001135154, NM_015359, NM_001351655, NM_001351656, NM_001351657, NM_001351658, NM_001351659, NM_001351660 |
Synonyms | cig19; HMNDYT2; LZT-Hs4; NET34; ZIP14 |
Summary | This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA108360 | SLC39A14 CRISPRa kit - CRISPR gene activation of human solute carrier family 39 member 14 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.