LY108 (SLAMF6) Human Gene Knockout Kit (CRISPR)
CAT#: KN420100
SLAMF6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
KN420100 is the updated version of KN220100.
USD 1,290.00
2 Weeks*
Size
Other products for "SLAMF6"
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | SLAMF6 |
Locus ID | 114836 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001184714, NM_001184715, NM_001184716, NM_052931 |
Synonyms | CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000 |
Summary | The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2010] |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
GA114477 | SLAMF6 CRISPRa kit - CRISPR gene activation of human SLAM family member 6 |
USD 1,290.00 |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.