Cyp24a1 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN504098

Cyp24a1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN504098 is the updated version of KN304098.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol Cyp24a1
Locus ID 13081
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_009996
Synonyms 24-OHase; CP24; Cyp24
Summary The protein encoded by this gene localizes to the mitochondrion, where it degrades calcitriol to calcitetrol. This gene is upregulated by binding of calcitriol to the upstream regulatory region and to a downstream enhancer region, thereby allowing calcitriol to autoregulate its concentration in the cell. The encoded protein may also play a role in calcium homeostasis. [provided by RefSeq, Aug 2015]

Other Versions

SKU Description Size Price
GA200974 Cyp24a1 CRISPRa kit - CRISPR gene activation of mouse cytochrome P450, family 24, subfamily a, polypeptide 1
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.