Trpc6 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN518295
Trpc6 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | Trpc6 |
Locus ID | 22068 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001282086, NM_001282087, NM_013838 |
Synonyms | AV025995; LLHWJM002; LLHWJM003; LLHWJM004; mtrp6; TRP-6; Trrp6 |
Summary | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion. [UniProtKB/Swiss-Prot Function] |
Documents
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Other Versions
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KN318295 | Trpc6 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN318295BN | Trpc6 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN318295LP | Trpc6 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN318295RB | Trpc6 - mouse gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA204457 | Trpc6 CRISPRa kit - CRISPR gene activation of mouse transient receptor potential cation channel, subfamily C, member 6 |
USD 1,290.00 |
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