Vldlr Mouse Gene Knockout Kit (CRISPR)

CAT#: KN518900

Vldlr - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.

SDS

KN2.0 knockout kit validation

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KN518900 is the updated version of KN318900.

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 2 gRNA vectors, 1 linear donor
Donor DNA EF1a-GFP-P2A-Puro
Symbol Vldlr
Locus ID 22359
Disclaimer The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001161420, NM_001347441, NM_013703
Synonyms AA408956; AI451093; AW047288
Summary Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
GA204604 Vldlr CRISPRa kit - CRISPR gene activation of mouse very low density lipoprotein receptor
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.