HMGN3 (NM_138730) Human Mass Spec Standard

CAT#: PH302339

HMGN3 MS Standard C13 and N15-labeled recombinant protein (NP_620058)

Product Images

Coomassie blue staining of purified HMGN3 protein (Cat# TP302339). The protein was produced from HEK293T cells transfected with HMGN3 cDNA clone (Cat# RC202339) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC202339
• Predicted MW: 8.4 kDa
• Protein Sequence:
  Sequence Link

  >RC202339 protein sequence
  Red=Cloning site Green=Tags(s)
  
  MPKRKSPENTEGKDGSKVTKQEPTRRSARLSAKPAPPKPEPKPRKTSAKKEPGAKISRGAKGKKEEKQEA
  GKEGTEN
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_620058
• RefSeq Size: 894
• RefSeq ORF: 231
• Synonyms: PNAS-24; PNAS-25; TRIP7
• Locus ID: 9324
• UniProt ID: Q15651
• Cytogenetics: 6q14.1
• Summary: The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]
• Protein Families: Druggable Genome