Mesothelin (MSLN) (NM_005823) Human Mass Spec Standard
CAT#: PH302532
MSLN MS Standard C13 and N15-labeled recombinant protein (NP_005814)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC202532 |
Predicted MW | 67.9 kDa |
Protein Sequence |
>RC202532 protein sequence
Red=Cloning site Green=Tags(s) MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQAAPLDGVLANPPNISSLSPRQLLGFPC AEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPLDLLLFLNPDAFSGPQACTRFF SRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSC PGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSW RQPERTILRPRFRREVEKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDV LKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQVATLIDRFVKG RGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSE YFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRD WILRQRQDDLDTLGLGLQGGIPNGYLVLDLSVQEALSGTPCLLGPGPVLTVLALLLASTLA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_005814 |
RefSeq Size | 2197 |
RefSeq ORF | 1869 |
Synonyms | MPF; SMRP |
Locus ID | 10232 |
UniProt ID | Q13421 |
Cytogenetics | 16p13.3 |
Summary | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401768 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC415604 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 187.00 |
|
LC429380 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY401768 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 1 |
USD 396.00 |
|
LY415604 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 |
USD 605.00 |
|
LY429380 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 |
USD 396.00 |
|
TP302532 | Recombinant protein of human mesothelin (MSLN), transcript variant 1 |
USD 867.00 |
|
TP723884 | Purified recombinant protein of Human mesothelin (MSLN), transcript variant 1 |
USD 205.00 |
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