Mesothelin (MSLN) (NM_005823) Human Recombinant Protein
CAT#: TP723884
Purified recombinant protein of Human mesothelin (MSLN), transcript variant 1
Product Images
Specifications
Product Data | |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence |
Human Mesothelin, the region of Glu296-Gly580, from gene Accession# NM_005823
|
Tag | C-His |
Predicted MW | 32.9 kDa |
Concentration | Protein formulated and vialed at >50 ug/mL in specified buffer |
Purity | >95%, as determined by Coomassie stained SDS-PAGE. |
Buffer | 1 x PBS, pH7.2 |
Bioactivity | The ED50 is 50-300 ng/ml, corresponding to a specific activity of 0.33-2.0 x 104 units/mg, determined by the dose dependent binding to CA125/MUC16 using a functional ELISA. |
Endotoxin | Less than 0.01 ng per µg protein as determined by the LAL method |
Storage | Store at -80°C. |
Stability | Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to 6 months, or at -70°C or below until the expiration date. Aliquots can be stored between 2°C and 8°C for up to one week and stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
Reference Data | |
RefSeq | NP_005814 |
Locus ID | 10232 |
UniProt ID | Q13421 |
Cytogenetics | 16p13.3 |
Refseq Size | 2197 |
Refseq ORF | 1869 |
Synonyms | MPF; SMRP |
Summary | This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401768 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 99.00 |
|
LC415604 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 155.00 |
|
LC429380 | MSLN HEK293T cell transient overexpression lysate (as WB positive control) |
USD 99.00 |
|
LY401768 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 1 |
USD 325.00 |
|
LY415604 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 |
USD 495.00 |
|
LY429380 | Transient overexpression lysate of mesothelin (MSLN), transcript variant 2 |
USD 325.00 |
|
PH302532 | MSLN MS Standard C13 and N15-labeled recombinant protein (NP_005814) |
USD 2,055.00 |
|
TP302532 | Recombinant protein of human mesothelin (MSLN), transcript variant 1 |
USD 867.00 |
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