PDE1B (NM_000924) Human Mass Spec Standard
CAT#: PH306588
PDE1B MS Standard C13 and N15-labeled recombinant protein (NP_000915)
Specifications
Product Data | |
Tag | C-Myc/DDK |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC206588 |
Predicted MW | 61.4 kDa |
Protein Sequence |
>RC206588 protein sequence
Red=Cloning site Green=Tags(s) MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNLEYTASLLEAV YIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFR RTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDA LETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKS ECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTAL QQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQS QIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQ ENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | 50 ug/ml as determined by BCA |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions. |
Reference Data | |
RefSeq | NP_000915 |
RefSeq Size | 3463 |
RefSeq ORF | 1608 |
Synonyms | HEL-S-79p; PDE1B1; PDES1B |
Locus ID | 5153 |
UniProt ID | Q01064, A0A024RB59 |
Cytogenetics | 12q13.2 |
Summary | 'The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]' |
Protein Families | Druggable Genome |
Protein Pathways | Calcium signaling pathway, Progesterone-mediated oocyte maturation, Purine metabolism |
Documents
FAQs |
Resources
Recombinant Protein Resources |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC400337 | PDE1B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LC431450 | PDE1B HEK293T cell transient overexpression lysate (as WB positive control) |
USD 121.00 |
|
LY400337 | Transient overexpression lysate of phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1 |
USD 396.00 |
|
LY431450 | Transient overexpression lysate of phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 2 |
USD 396.00 |
|
TP306588 | Recombinant protein of human phosphodiesterase 1B, calmodulin-dependent (PDE1B) |
USD 823.00 |
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