CYP51A1 (NM_000786) Human Mass Spec Standard

CAT#: PH307078

CYP51A1 MS Standard C13 and N15-labeled recombinant protein (NP_000777)

  View other "CYP51A1" proteins (1)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC207078
Predicted MW 57.3 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_000777
RefSeq Size 3208
RefSeq ORF 1527
Synonyms CP51; CYP51; CYPL1; LDM; P450-14DM; P450L1
Locus ID 1595
UniProt ID Q16850, A0A0C4DFL7
Cytogenetics 7q21.2
Summary 'This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]'
Protein Families Druggable Genome, P450, Transmembrane
Protein Pathways Metabolic pathways, Steroid biosynthesis

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