Peroxiredoxin 2 (PRDX2) (NM_181738) Human Mass Spec Standard

CAT#: PH309548

PRDX2 MS Standard C13 and N15-labeled recombinant protein (NP_859428)

Product Images

Coomassie blue staining of purified PRDX2 protein (Cat# TP309548). The protein was produced from HEK293T cells transfected with PRDX2 cDNA clone (Cat# RC209548) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC209548
• Predicted MW: 15.6 kDa
• Protein Sequence:
  Sequence Link

  >RC209548 representing NM_181738
  Red=Cloning site Green=Tags(s)
  
  MASGNARIGKPAPDFKATAVVDGAFKEVKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSNRAEDFRKLGC
  EVLGVSVDSQFTHLAWYEQGPKREVAAKLTPSGPSSVASWPLLNLWNLRFPIVKIMETLPPKSLRMMTVI
  SI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_859428
• RefSeq Size: 710
• RefSeq ORF: 426
• Synonyms: NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
• Locus ID: 7001
• Cytogenetics: 19p13.13
• Summary: 'This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]'
• Protein Families: Druggable Genome