KCNIP4 (NM_025221) Human Mass Spec Standard

CAT#: PH311488

KCNIP4 MS Standard C13 and N15-labeled recombinant protein (NP_079497)

Product Images

Coomassie blue staining of purified KCNIP4 protein (Cat# TP311488). The protein was produced from HEK293T cells transfected with KCNIP4 cDNA clone (Cat# RC211488) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC211488
• Predicted MW: 28.5 kDa
• Protein Sequence:
  Sequence Link

  >RC211488 representing NM_025221
  Red=Cloning site Green=Tags(s)
  
  MNVRRVESISAQLEEASSTGGFLYAQNSTKRSIKERLMKLLPCSAAKTSSPAIQNSVEDELEMATVRHRP
  EALELLEAQSKFTKKELQILYRGFKNECPSGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAV
  SFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAPRQHVE
  TFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFENVI
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_079497
• RefSeq Size: 1556
• RefSeq ORF: 750
• Synonyms: CALP; KCHIP4
• Locus ID: 80333
• UniProt ID: Q6PIL6
• Cytogenetics: 4p15.31-p15.2
• Summary: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
• Protein Families: Druggable Genome, Ion Channels: Other