PIK3AP1 (NM_152309) Human Mass Spec Standard

CAT#: PH314125

PIK3AP1 MS Standard C13 and N15-labeled recombinant protein (NP_689522)

  View other "PIK3AP1" proteins (3)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC214125
Predicted MW 90.2 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_689522
RefSeq Size 4817
RefSeq ORF 2415
Synonyms BCAP
Locus ID 118788
UniProt ID Q6ZUJ8, Q86YV3
Cytogenetics 10q24.1
Summary Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. [UniProtKB/Swiss-Prot Function]
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway

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