CLIC1 (NM_001288) Human Mass Spec Standard

CAT#: PH318042

CLIC1 MS Standard C13 and N15-labeled recombinant protein (NP_001279)

Product Images

Coomassie blue staining of purified CLIC1 protein (Cat# TP318042). The protein was produced from HEK293T cells transfected with CLIC1 cDNA clone (Cat# RC218042) using MegaTran 2.0 (Cat# TT210002).

Specifications

Product Data

• Tag: C-Myc/DDK
• Species: Human
• Expression Host: HEK293
• Expression cDNA Clone or AA Sequence: RC218042
• Predicted MW: 26.7 kDa
• Protein Sequence:
  Sequence Link

  >RC218042 representing NM_001288
  Red=Cloning site Green=Tags(s)
  
  MAEEQPQVELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFNVTTVDTKRRTETVQKLCPGGQLPFLLYG
  TEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVL
  DNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYL
  SNAYAREEFASTCPDDEEIELAYEQVAKALK
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: 50 ug/ml as determined by BCA
• Labeling Method: Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
• Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.

Reference Data

• RefSeq: NP_001279
• RefSeq Size: 1265
• RefSeq ORF: 723
• Synonyms: CL1C1; G6; NCC27
• Locus ID: 1192
• UniProt ID: O00299, Q5SRT3
• Cytogenetics: 6p21.33
• Summary: 'Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. [provided by RefSeq, Jul 2008]'
• Protein Families: Druggable Genome, Ion Channels: Other