SETDB1 (NM_001145415) Human Mass Spec Standard

CAT#: PH326620

SETDB1 MS Standard C13 and N15-labeled recombinant protein (NP_001138887)

  View other "SETDB1" proteins (7)

USD 2,055.00

3 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Tag C-Myc/DDK
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC226620
Predicted MW 143 kDa
Protein Sequence
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration 50 ug/ml as determined by BCA
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 100 mM glycine, 25 mM Tris-HCl, pH 7.3. Store at -80°C. Avoid repeated freeze-thaw cycles. Stable for 3 months from receipt of products under proper storage and handling conditions.
Reference Data
RefSeq NP_001138887
RefSeq ORF 3873
Synonyms ESET; H3-K9-HMTase4; KG1T; KMT1E; TDRD21
Locus ID 9869
UniProt ID Q15047
Cytogenetics 1q21.3
Summary This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described. [provided by RefSeq, Jun 2011]
Protein Families Druggable Genome
Protein Pathways Lysine degradation

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.