Apolipoprotein B / Apo B Human Protein

CAT#: BA054

Apolipoprotein B / Apo B human protein, 0.5 mg


USD 260.00

5 Days*

Size
    • 500 ug

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Other products for "APOB"

Specifications

Product Data
Species Human
Protein Source Plasma
Concentration lot specific
Purity >95% Column chromatography.
single arc by IEP against whole human serum.
Buffer Presentation State: Purified
State: Lyophilized purified fraction(>95% pure by SDS-PAGE).
Buffer System: 50 mM Na2CO3, pH 10.0, 50 mM NaCl containing 10 mM Sodium Deoxycholate.
Reconstitution Restore with 258 µl distilled water.
Preparation Lyophilized purified fraction(>95% pure by SDS-PAGE).
Protein Description Purified human Apo-B
Note Caution: All human source materials have tested negative for HIV 1, HIV 2, anti-HCV, anti-HBc antibodies and HBsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.
Storage Store the antigen at -20°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000375
Locus ID 338
Cytogenetics 2p24.1
Synonyms apoB-48; apoB-100; FCHL2; FLDB; LDLCQ4
Summary 'This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins (LDL), and is the ligand for the LDL receptor. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Dec 2019]'
Protein Families Druggable Genome, Transmembrane

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.