Collagen type VI Human Protein

CAT#: RA011

Collagen type VI human protein, 0.5 mg


USD 430.00

5 Days*

Size
    • 500 ug

Product Images

Other products for "COL6A1"

Specifications

Product Data
Species Human
Protein Source Placenta
Concentration lot specific
Purity Chromatographically and Immunologically pure.
Buffer State: Liquid (sterile filtered) fraction.
Buffer System: 0.5 M Acetic Acid, containing 0.01% (w/v) Sodium Azide as preservative.
Preparation Liquid (sterile filtered) fraction.
Applications For use as a Control or Standard in Indirect trapping ELISA for quantitation of antigen in serum using a standard curve, for immunoprecipitation and for Wwestern blotting.
Protein Description Collagen type VI, prepared from human placenta, is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins. This product reacts with anti-Collagen Type VI. Reaction with anti-Collagen I, II, III, IV or V is negligible (typically less than 1% cross reactivity was detected by ELISA).
Note Caution: Source material supplied to your facility has been tested for the detection of HIV antibody, Hepatitis B surface antigen, antibody to Hepatitis C, HIV 1 antigen(s), antibody to HTLV - I/II, and syphilis with FDA approved test kits. All units were found to be non-reactive/negative for these tests. Nevertheless, all products from human sources should be handled as potentially infectious.
Storage Store vial at 2-8°C prior to opening.
This product is stable 2-8°C as an undiluted liquid.
Dilute only prior to immediate use.
Stability Shelf life: six (6) months from despatch.
Reference Data
RefSeq NP_001839
Locus ID 1291
Cytogenetics 21q22.3
Synonyms BTHLM1; OPLL; UCHMD1
Summary 'The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]'
Protein Pathways ECM-receptor interaction, Focal adhesion

Documents

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.